Metagenomics & metatranscriptomics: the dental microbiome and caries
Impact of HIV on childhood caries
Arginine catabolism and dental health
Global patterns of exchange for antibiotic genes
Phylogenomics: resolving the Streptococcus mitis and Streptococcus oralis species complex
Metagenomics: the fungal mycobiome and caries
Phylogenomics: bacterial ribosomal genes
Metagenomics: Legionnaires' disease
Streptococcus agalactiae: adaptation and movement among hosts and niches
High gene diversity for Campylobacter membrane polysacharides
Compatative genomics for an opportunistic pathogen of cats and dogs
Genome evolution and functional diversity for the Streptococci
The current emphasis of my laboratory is the association between microbiomes and human health. Specific topics include (i) the supragingival microbiome and the impact of HIV infection on childhood caries, (ii) the urethra microbiome and the impact of menopause on recurrent urinary tract infections, and (iii) the microbiome within water cooling towers and its relationship with Legionnaires' Disease. For human associated microbiomes, we are particularly interested in developing high resolution DNA sequencing approaches to elucidate strain level taxonomic diversity dynamics and metabolic activity within these ecosystems.
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2020 Junior Researcher of the Year
Department of Biological Sciences, College of Science, Clemson University, Clemson, SC 29634